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What is Lumen in Biology? 

A lumen in biology refers to the inside space of a tabular structure such as an intestine or artery. Lumen comes from a Latin word that means “an opening”. For example, the endoplasmic reticulum lumen refers to the space inside the folds of ER.  

It refers to the vessel’s interior as a central space in a vein or artery through which the blood flows.  

A lumen can also be the inside space of a cellular structure such as the endoplasmic reticulum.  

It refers to: 

  • Vessel’s interior 
  • Pathways of bronchi in lungs 

When talking about cell biology, a lumen is a membrane-defined space that is found inside several organelles.

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